Samson Nivins

Following are the notes taken from the Lecture given by Prof. Sally Rogers, UC Davis in UoA, New Zealand. The main highlight of the lecture was the early intervention, how you can easily classify and identify. How, they could be intervened earlier, so that they get best of the treatment. " Turn up the volume of social contest"- By Rogers The most important fact she discussed is that, kids with this disorder are lack of Imitation skills. She has proved that through literature's, children who has better imitation skills show better outcome.Moreover, How to make the kid to improvise the skills. She demonstrated with a therapist just making a task of "playing the single drum", with a 2 year kid. 1. She started the task, and followed by kid responded 2. She gave single word command like go, stop, slow, fast 3. The kid followed systematically, what the therapist did 4. She followed assendo manner of increasing and decreasing the speed 5. Positive response o

[ 18 F] 2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography scan was performed on 45 children with autism to study the baseline pattern and age-related developmental changes in the brain metabolism. Median standardized uptake values (SUVs) were compared with published healthy control data. Results showed that, in contrary to control data, the median SUVs in children with autism decrease linearly with increase in age. As compared to controls, autism children below 5 years showed greater metabolism and older children showed lower metabolism. In autism group, comparison of absolute SUVs within different regions of the brain revealed relatively lower metabolism in amygdala, hippocampus, parahippocampal gyrus, caudate nucleus, cerebellum, mesial temporal lobe, thalamus, superior and middle temporal pole, and higher metabolic uptake in calcarine fssure and Heschl’s gyrus. These results help in understanding the baseline metabolism and developmental changes of brain

Abstract Brain undergoes most of the dynamic change in utero and the developmental changes continue over the first two postnatal years of life. Early phase of life is very crucial as neurodevelopmental disorder such as Autism, ADHD are likely to be noticeable during the first years of life. Better understanding of normal brain pattern is necessary for identifying abnormal developmental pattern. In the present case, a typical neurologically normal infant was scanned using 18 F-FDG PET during its sixth and ninth months. At sixth month, infant showed maximum 18 F-FDG uptake in subcortical structures including basal ganglia and thalamus. After three months follow-up from the baseline the infant showed increased 18 F-FDG uptake globally. Basal ganglia, thalamus and visual cortices showed maximum 18 F-FDG uptake compared to other regions of the brain, while medial temporal cortex and cerebellum showed the minimum 18 F-FDG uptake. The present case demonstrates the brain 18 F-FDG uptake in a

Abstract   Background: Early phase of the life are very dynamic and important for postnatal brain development. Better understanding of the normal growth pattern is essential to identify the abnormal pathogenesis of different neurological disorders. Materials and Method: In the present case report brain glucose metabolic pattern of a one year neurologically normal infant was scanned using Positron emission tomography (PET) with [18F] fluoro-2-deoxy-D-glucose (FDG) with a 3 month of follow-up. Results: During the baseline scan, frontal cortex showed comparatively greater SUVs when compared to other cortical and subcortical regions. During the follow-up scan, an increase in SUVs were seen in all regions. When the brain FDG-PET was visually accessed during the baseline maximum FDG uptake was seen in bilateral middle frontal cortex and occipital cortex. During the follow-up scan frontal cortex, posterior cingulate cortex, basal ganglia and occipital cortex showed maximum FDG uptake, t