Basal ganglia crcuitry

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Coronavirus disease 2019 (COVID-19) - Structure

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Origin -  C ity of Wuhan, Hubei Province, Central China In early December 2019, numerous people with unknown causes of pneumonia were observed in  Wuhan City, Hubei Province, Central China. Then, scientists studied the genome of the virus and named 'coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).  The primary (main) site of infection-  The virus was identified in the respiratory tract of the patients  Structure -  SARS-CoV-2 is an enveloped, non-segmented, positive-sense RNA virus that is within the sarbecovirus, ortho corona virinae subfamily found in humans, and other mammals. It's about 65-125nm in diameter, containing single strands of RNA and provided with crown-like spikes on the outer surface.  Structurally, it has four main proteins Spike (S) glycoprotein Small envelope (E) glycoprotein Membrane (M) protein  Nucleocapsid ...
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Normal Brain Glucose Metabolism in Neonates

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Abstract   Background: Early phase of the life are very dynamic and important for postnatal brain development. Better understanding of the normal growth pattern is essential to identify the abnormal pathogenesis of different neurological disorders. Materials and Method: In the present case report brain glucose metabolic pattern of a one year neurologically normal infant was scanned using Positron emission tomography (PET) with [18F] fluoro-2-deoxy-D-glucose (FDG) with a 3 month of follow-up. Results: During the baseline scan, frontal cortex showed comparatively greater SUVs when compared to other cortical and subcortical regions. During the follow-up scan, an increase in SUVs were seen in all regions. When the brain FDG-PET was visually accessed during the baseline maximum FDG uptake was seen in bilateral middle frontal cortex and occipital cortex. During the follow-up scan frontal cortex, posterior cingulate cortex, basal ganglia and occipital cortex showed maximum FDG uptak...
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An apple and the aged brain

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An apple can be compared to a human brain. If you zoom the apple, very carefully, you will observe that the apple is getting near to the expiry date (older & rotten). Similarly, you can compare with an aged brain (beyond a threshold +65), where you would see shrinkage in the brain with an intrinsic curvature (As you see in the apple). Lol. Don't think, I am funny, but that's the fact. Be happy!! Weekend vibes. ☕☕☕
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