Samson Nivins

Abstract Brain undergoes most of the dynamic change in utero and the developmental changes continue over the first two postnatal years of life. Early phase of life is very crucial as neurodevelopmental disorder such as Autism, ADHD are likely to be noticeable during the first years of life. Better understanding of normal brain pattern is necessary for identifying abnormal developmental pattern. In the present case, a typical neurologically normal infant was scanned using 18 F-FDG PET during its sixth and ninth months. At sixth month, infant showed maximum 18 F-FDG uptake in subcortical structures including basal ganglia and thalamus. After three months follow-up from the baseline the infant showed increased 18 F-FDG uptake globally. Basal ganglia, thalamus and visual cortices showed maximum 18 F-FDG uptake compared to other regions of the brain, while medial temporal cortex and cerebellum showed the minimum 18 F-FDG uptake. The present case demonstrates the brain 18 F-FDG uptake in a

Abstract   Background: Early phase of the life are very dynamic and important for postnatal brain development. Better understanding of the normal growth pattern is essential to identify the abnormal pathogenesis of different neurological disorders. Materials and Method: In the present case report brain glucose metabolic pattern of a one year neurologically normal infant was scanned using Positron emission tomography (PET) with [18F] fluoro-2-deoxy-D-glucose (FDG) with a 3 month of follow-up. Results: During the baseline scan, frontal cortex showed comparatively greater SUVs when compared to other cortical and subcortical regions. During the follow-up scan, an increase in SUVs were seen in all regions. When the brain FDG-PET was visually accessed during the baseline maximum FDG uptake was seen in bilateral middle frontal cortex and occipital cortex. During the follow-up scan frontal cortex, posterior cingulate cortex, basal ganglia and occipital cortex showed maximum FDG uptake, t